Genetics question help please?

If there was a genome consisting of a million bas pairs of double stranded DNA containing 25% A,25% C, 25% G, 25% T in a random order.Whats the probability that base 1 is an A and base 2 is a T? and that basis 1-21 are identical to one of the sequences Met-Tyr-Gly-Glu-Asn-Glu?